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Beyond Wonderland: The Endless Sea will be taking over the NOS Events Center on Friday, March 24, and Saturday, Main San Bernardino, CA. #Beyond wonderland 2017 dates full#No date has been set for Beyond Wonderland 2017 but we’re sure to hear news real soon as 2016 comes to an end.īeyond Wonderland SoCal will see Alice and the Queen embark on a strange and wondrous new voyage, but is returning to its original home at the NOS. Finally, the fan-favorite Upside Down House will be taken over by the Insomniac Records crew, with artists like Aazar, Gladiator, JSTJR, Redlight, and Sinden keeping the music right on the decks. Beyond Wonderland is coming to the Gorge Amphitheatre Join Alice and a curious cast of characters for three nights of camping and two full days of electronic dance music, immersive art, costumed performers, and more. Now, in a recent Facebook post from Pasquale Rotella, co-founder and CEO of Insomniac Events, Rotella has announced Beyond Wonderland 2017 will take place at the beloved NOS Events Center, just like the good ol’ days and where this festival orginally started at. Beyond Wonderland is an electronic music festival that uses a story-telling angle to set a context for a fantasy electronic music festival. London, 27 November 2020 Playtech, the world’s leading gambling technology company, has launched a unique new concept in Live Casino gaming with Adventures Beyond Wonderland exclusively released on GVC Holdings (to be renamed Entain plc) brands, in the UK and across. Beyond Wonderland 2015 returned to the San Manuel Amphitheater, rightfully so as it was the first Insomniac Event to make the transition from the usual ‘warehouse’ vibes of the NOS Center to the wide, green ranges of San Manuel, which saw Insomniac bring their biggest stage production to life at this beautiful venue. With Beyond Wonderland’s absence in 2014, Pasquale Rotella and his Insomniac Events team took the city of San Bernardino by storm curating a new two-day, camping experience for the very first time for this particular festival. #Beyond wonderland 2017 dates free#We saw Beyond take place at the NOS for three years till it was moved to a greener venue in 2013 giving life to a whole new concept of getting lost in wonderland. Vibe Team March.31. The Admission-Free Santa Cruz Beach Boardwalk Enjoy warm sand, cool surf, hot rides and free entertainment at the only major seaside amusement park on the. Thus Beyond Wonderland was born on Saturday, March 20th, 2010 at the legendary NOS Events Center. #Beyond wonderland 2017 dates pro#A pro tip from the gorgeous to make sure you’re parking in Insomniac parking lots! Insomniac lots are monitored during the whole event, whereas others aren’t necessarily as tightly run and you run the risk of getting your car broken into. We always want everyone to have a great time, and even though the majority of us spread PLUR, there are unfortunately those who aren’t always spreading those same vibes.Back in 2010, Insomniac gave birth to a brand new concept that was strictly dedicated to the Alice In Wonderland theme after Nocturnal Wonderland (at the time Nocturnal Festival) was more dedicated to the darker side of the rabbit hole and went in a new direction and far away from Alice. For more information, visit the official website. If you’re not familiar with the NOS Event center then make sure you’re preparing properly! AKA: Make sure you know where you’re going to park/ how you’re going to get there. Beyond Wonderland 2017 takes place Friday, March 24, and Saturday, March 25, at the NOS Events Center in San Bernardino, CA. Billups When global music producer Insomniac announced in May that it was first hosting the Beyond Wonderland electronic dance music festival in the Pacific Northwest, and in particular the Gorge Amphitheater, this fan’s heart was Long-standing EDM has skipped 100,000 BPM. I can’t wait to see the Insomniac interpretation of Alice and her merry band of misfits! This reimagined version of the seventh annual Beyond Wonderland SoCal will take place Friday, March 24th, and Saturday, March 25th with tickets for this Spring voyage still available now. Last year they created a magical underwater world, including twinkling sea lanterns, vibrant coral reefs, and mermaids For this year they have something out of a storybook. Beyond Wonderland will return to NOS Events Center in San Bernardino, California this 2017 for a brand new rendition: The Endless Sea. Beyond Wonderland 2017 takes place Friday, March 24, and Saturday, March 25, at the NOS Events Center in San Bernardino, CA. The Insomniac crew has created an immersive experience for their headliners, including all new stage productions, art installations, and other-worldly character and aerial costumes. Join us in this magical adventure to the Endless Sea grab your tickets for Beyond Wonderland 2017 now. These hormones play an essential role in humans and take part in controlling the rate of the heart, digestion, muscle contraction, and cell metabolism. Small amounts of iodine minerals are necessary for the production of vital thyroid hormones. Here is a quick video that demonstrates the liquid state of iodine: By carefully controlling the temperature, so that it sits just above the melting point, one can visibly see the process of iodine melting. Second, iodine’s liquid state can be difficult to see The vapor cloud’s intense violet color completely overwhelms the liquid.Īs shown in the diagram, there is a point where the liquid and vapor states exist at the same time. This makes it easy to explain how solid iodine can just simply vaporize. Two factors feed into this misconception: First, iodine is very volatile. At normal pressures and at a temperature range of about 113.6˚C to 184.4˚C (236.48˚F to 363.92˚F), iodine exists as a liquid. There is a large misconception about how iodine can not be a liquid, an idea that even some textbooks are guilty of teaching. Many believe that under these conditions, solid iodine will sublimate into gas. For iodine, the triple point is 113.5˚C at 12.1 kPa. This is an endothermic transition and only occurs when the temperature and pressure are below the triple zero. When a solid sublimates, it directly transforms into vapor, completely skipping the liquid phase. What is sublimation? Usually, when a solid vaporizes, it first has to melt into a liquid. Furthermore, thyroxine, a secretion of the thyroid gland in humans, contains iodine. In addition to the Earth’s crust, this element is in seawater. Out of the halogen family, iodine is the least abundant. KI acts to decrease the vapor pressure and to dilute iodine to make it safer. More specifically, this element reacts well with solutions containing potassium iodide (KI + I 2 → KI 3). However, it reacts oppositely towards aqueous solutions of iodide, where it is very soluble. Out of the halogen family, iodine is the least soluble in water, with a solubility value of 0.03 grams per 100 grams of water. Still, it has the greatest reducing strength and readily gains electrons from other atoms. However, compared to its family members, iodine is relatively less reactive. All halogens are highly electronegative and very reactive. The element iodine belongs to the halogen family, along with fluorine, chlorine, bromine, and astatine. The iodine atom has an electron configuration of 4d 105s 25p 5, or 1s 22s 22p 63s 23p 63d 104s 24p 64d 105s 25p 5 Iodine vs Other Halogens Its aqueous chemistry is similar to bromine’s. Iodine lies below bromine, above astatine, to the right of tellurium, and to the left of xenon. Iodine, with atomic symbol I, is a nonmetal that lies in group 17 of the periodic table, the halogens.
Nevertheless, day to day relations were conducted on the basis of generosity, consideration, and gentleness towards others. Individual freedom, exemplified by liberation or enlightenment, was the primary focus of the entire community and was achieved by cultivating the mind in meditation. The only slight difference in status depended on seniority of ordination. Within this fraternity, individuals were equal, whatever their social class or caste origins. The institution the Buddha established was the Sangha or monastic community, which functioned on largely democratic lines. Not only do we all desire happiness and seek to avoid suffering, but each of us has an equal right to pursue these goals. Irrespective of whether we are rich or poor, educated or uneducated, belonging to one nation or another, to one religion or another, adhering to this ideology or that, each of us is just a human being like everyone else. Buddhism too recognises that human beings are entitled to dignity, that all members of the human family have an equal and inalienable right to liberty, not just in terms of political freedom, but also at the fundamental level of freedom from fear and want. Modern democracy is based on the principle that all human beings are essentially equal, that each of us has an equal right to life, liberty, and happiness. He also saw that while ignorance binds beings in endless frustration and suffering, wisdom is liberating. The Buddha saw that life's very purpose is happiness. A goal to be attained by men and women alike. As Buddhists, we Tibetans revere human life as the most precious gift and regard the Buddha's philosophy and teaching as a path to the highest kind of freedom. The idea that people can live together freely as individuals, equal in principle and therefore responsible for each other, essentially agrees with the Buddhist disposition. Just as the introduction of Buddhism to Tibet cemented our nation, I am confident that the democratization of our society will add to the vitality of the Tibetan people and enable our decision-making institutions to reflect their heartfelt needs and aspirations. I believe that future generations will consider these changes among the most important achievements of our experience in exile. Our democratization has reached out to Tibetans all over the world. I hope that these moves will allow the people of Tibet to have a clear say in determining the future of their country. There are many advantages to such a step and it will enable us to become a true and complete democracy. The future head of the Tibetan Government must be someone popularly elected by the people. For many reasons, I have decided that I will not be the head of, or play any role in the government when Tibet becomes independent. We have recently embarked on changes that will further democratize and strengthen our administration in exile. A democracy that has nonviolence and peace at its roots. I have long looked forward to the time when we could devise a political system, suited both to our traditions and to the demands of the modern world. The familiarity of all Tibetan exiles with the word 'democracy' shows this. Over the years, therefore, we have tried through various means to achieve a model of true democracy. Therefore, those of us in exile have had a responsibility to contemplate and plan for a future Tibet. Our brothers and sisters in Tibet, despite being in their own country do not even have the right to life. Later, we learned the hard way that in the international arena, as well as at home, freedom is something to be shared and enjoyed in the company of others, not kept to yourself.Īlthough the Tibetans outside Tibet have been reduced to the status of refugees, we have the freedom to exercise our rights. We hardly noticed when India, one of our closest neighbours, having peacefully won her independence, became the largest democracy in the world. Consequently, we paid little attention to the changes taking place in the world outside. When Tibet was still free, we cultivated our natural isolation, mistakenly thinking that we could prolong our peace and security that way. The emergence of peoples' power movements, overthrowing dictatorships of left and right, has shown indisputably that the human race can neither tolerate nor function properly under tyranny.Īlthough none of our Buddhist societies developed anything like democracy in their systems of government, I personally have great admiration for secular democracy. However, because people have an innate desire for freedom, the forces of liberty and oppression have been in continuous conflict throughout history. For thousands of years people have been led to believe that only an authoritarian organization employing rigid disciplinary methods could govern human society. We tested the hypothesis that renal transplant patients with early posttransplant AVR have significantly higher anti-LG3 titers than patients with nonvascular acute rejection episodes or normal allograft function. In this work, we tested the possibility that LG3 behaves as a neoantigen, fuelling the production of anti-LG3 antibodies of potential importance in regulating allograft vascular inflammation and injury. Increased serum and urinary LG3 levels were also found in renal transplant patients with AVR 16 and chronic allograft nephropathy 17. Our group showed that endothelial apoptosis triggers perlecan proteolysis and production of a truncated C-terminal perlecan fragment, LG3, which in turn accelerates vascular obliteration in a murine model of vascular rejection 15, 16. 12 How this autoimmune response shapes and/or accelerates alloimmune recognition is only beginning to be appreciated.ĪVR leads to severe microvascular injury and enhanced endothelial apoptosis of potential importance in the production or modification of antigenic targets 13, 14. For instance, the presence of antiagrin antibodies is associated with chronic transplant glomerulopathy and a higher number of prior acute rejection episodes in KTR. Antibodies targeting vascular basement membrane components have also been linked with adverse transplant outcomes. Antibodies against vimentin have been associated with accelerated acute heart rejection in animal models of cardiac transplantation 9 and with chronic rejection of heart 10 and kidney 11 allografts in human transplant recipients. Agonistic antibodies for the angiotensin type 1 receptor (AT 1R) were identified in KTR with refractory AVR and severe hypertension 7, as well as in DSA negative patients with antibody-mediated rejection 8. In KTR, antibodies against the polymorphic MHC class I-related chain A (MICA) and B (MICB) have been associated with increased rates of acute rejection and reduced graft survival 6. While the importance of donor-specific anti-HLA antibodies in kidney transplantation cannot be overstated, antibodies directed toward non-HLA epitopes can contribute to acute or chronic allograft rejection 4, 5. This suggests that factors, yet to be described, modulate the destructive potential of anti-HLA antibodies on renal allografts. Positive DSA detected in long-term kidney transplant recipients (KTR) is a somewhat less dramatic condition but nonetheless associated with progressively declining renal function and reduced allograft survival 3. Detectable donor-specific anti-HLA antibodies (DSA) at the time of transplantation or in the early posttransplantation period are the main factor implicated in severe AVR episodes that will rapidly destroy the allograft if not controlled by plasmapheresis and B-cell depleting therapy 2. Collectively, these data identify anti-LG3 antibodies as novel accelerators of immune-mediated vascular injury and obliterative remodeling.Īcute vascular rejection (AVR) of renal allografts is a relatively uncommon yet dramatic condition requiring aggressive immunosuppression and associated with a high rate of permanent graft dysfunction and loss 1. Neointima formation, C4d deposition and allograft inflammation were significantly increased in recipients of an ischemic aortic allograft passively transferred with anti-LG3 antibodies. To address the functional role of anti-LG3 antibodies in AVR, we turned to passive transfer of anti-LG3 antibodies in an animal model of vascular rejection based on orthotopic aortic transplantation between fully MHC-mismatched mice. Elevated pretransplant anti-LG3 titers (OR: 4.62, 95% CI: 1.08–19.72) and pretransplant donor-specific antibodies (DSA) (OR 4.79, 95% CI: 1.03–22.19) were both independently associated with AVR. Patients who experienced AVR had elevated anti-LG3 titers pre and posttransplantation compared to subjects with ATIR or stable graft function (p < 0.05 for both mediators). We performed a case–control study in which we compared anti-LG3 IgG titers in kidney transplant recipients with AVR (n = 15) versus those with acute tubulo-interstitial rejection (ATIR) (n = 15) or stable graft function (n = 30). Here, we tested the possibility that LG3 behaves as a neoantigen, fuelling the production of anti-LG3 antibodies of potential importance in regulating allograft vascular injury. We reported previously that apoptotic ECs release a bioactive C-terminal fragment of perlecan referred to as LG3. Acute vascular rejection (AVR) is characterized by immune-mediated vascular injury and heightened endothelial cell (EC) apoptosis. Head online to challenge other players with 35 different civilizations in your quest for world domination throughout the ages.Ĭhoose your path to greatness with this definitive remaster to one of the most beloved strategy games of all time.Īge of Empires II: Definitive Edition, 4K graphics and 4 new civilizations. 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Build cities, manage resources, and lead your troops to battle on land and at sea in 4 distinct campaigns with 35 missions that span across 500 years of history from the Dark Ages up to the Renaissance. Return to History – The past is prologue as you are immersed in a rich historical setting of 8 diverse civilizations across the world from the English to the Chinese to the Delhi Sultanate in your quest for victory. nunca llegu a terminarlo, pues siempre he perdido la partida por. Ya era hora de que hicieran una remasterizacin de este clsico, para m es el mejor de todos los age of empires, sobre todo por su sencillez a la hora de construir los castillos. Gran resolucin de los personajes de age of empires 2 hd edition Eve green. desafía a tus amigos con cuatro civilizaciones adicionales, nuevas unidades, tecnologías y construye tu imperio tanto en el agua como en la tierra. ltimas Opiniones Sobre Age of Empires II HD Edition. 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A custom ATmega32u4 board I decided to make my own ATmega32u4-based microcontroller board for several reasons.Reflow hot plate controller board Description:This project realizes a custom made reflow hot plate controller. TCD1304 miniature PCB In this project, I continued working with the TCD1304 linear CCD.Weighing scale made of a PCB In this project, I wanted to try something new and fun.First, I wanted to know if I can use the trac.Custom ADS1256 board with ATmega32U4 I created my own ADS1256 PCB after working with this AD converter for several years. REFLOW PCB CODEAlso, check my website for extra resources and a video explaining the board.Ĭheck the following video where I explain everything about the board, the heater and I explain the source code line by line: REFLOW PCB ZIPThere is a very useful interactive BOM file in the attached zip file. Replace it if you use a larger load.įor all the parts and the values, check the attached BOM file. The varistor (PTC) I picked (SIOV-S05K250) is sized for 5 A.Also, leave a little gap between the PCB and the heatsink because one of the 230 V trace is running under the heatsink. Use a mica sheet is something similar between the TRIAC and the heat sink. The TRIAC must be isolated from the heatsink.Keep in mind that the TRIAC-side resistors must be high power resistors 1 W at least.I suggest to solder the MAX6675 module, the rotary encoder and the display directly to the PCB.You can also attach a tiny heatsink to the BD139 transistor, but probably it is not necessary because it switches relatively low power.Keep in mind that the TRIAC I picked is "only" a 8 A one. You can add a larger heatsink to the TRIAC if you want to use it with high-power heaters.Typically, the 5 V brick provides 600 mA and the 12 V provides 250 mA. Based on the selected power brick (5 V or 12 V), you have to choose the fans carefully to stay within the specifications of the power brick. REFLOW PCB PLUSThe board has 4 mounting pads at the (rounded) corners, plus there is a protective earth connection that allows an easy connection to the metal parts that should be grounded. The high-current traces are at the bottom of the PCB, there is only a few high-voltage (230 V) traces on the top side and they do not carry large currents, they are only used for the switching the TRIAC. I added some gaps to the board to avoid arching at critical places. The switching of the heater is done by an optocoupler-TRIAC combo. The system also contains two outputs for fans, so at the end of the heating program, a forced cooling can be applied. The temperature is measured with a thermocouple via a MAX6675 module. All the parameters can be set with a rotary encoder. temperature graph is shown on a 1.8" LCD. The programmable reflow curve and the real-time time vs. I made a fancy graphical user interface for programming the heating curve and displaying the temperature in real time. This project realizes a custom made reflow hot plate controller. |
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